HD-EEG source imaging with simultaneous SEEG recording in drug-resistant epilepsy.

ABSTRACT:

Objective

This study aimed to assess the complementary role of high-density electroencephalography (HD-EEG)-based electrical source imaging (ESI) in localizing the seizure-onset zone (SOZ) during ictal events and the irritative zone (IZ) during the interictal period, using simultaneous acquired stereo-EEG (SEEG) recordings as a reference. In addition, we investigated the relationship of ictal cortical source activity with their scalp and intracranial EEG correlates, focusing on factors influencing ESI accuracy.

Methods

We enrolled 29 patients with drug-resistant epilepsy who underwent simultaneous HD-EEG and SEEG recordings. ESI was performed on ictal and interictal discharges of HD-EEG identified via SEEG, and localization accuracy was assessed relative to SEEG-defined sour

SUBMITTER: Hao S 

PROVIDER: S-EPMC12661267 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature