<i>Enterococcus faecium B13</i> Affects Mice Growth by Regulating Gut Microbiota and Metabolites.

ABSTRACT: Gut microbiota can influence the growth performance of animals. In our previous study, Enterococcus faecium B13 exhibited promoting growth in piglets. This study aimed to reveal the mechanism underlying the growth promotion. Therefore, B13 was administered to male mice via oral gavage, and the growth performance, gut microbiota, and metabolites were analyzed. Results showed that the weight gain trend in the B13 group was slightly higher than in the control group during 28 days, and the serum triglycerides (TG) level was significantly lower in the B13 group (p < 0.05). Notably, the microbial composition differed between the two groups. The ratio of Firmicutes/Bacteroidetes (F/B) rose in the colon. The Allobaculum and Alloprevotella, which promoted growth a

SUBMITTER: Luo F 

PROVIDER: S-EPMC12661549 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature