Abnormal Connectivity of the Head Neural Integrator in Cervical Dystonia.

ABSTRACT:

Background

Cervical dystonia is characterized by abnormal neck and head movements, possibly related to a dysfunction of the interstitial nucleus of Cajal (INC) and the head neural integrator, a system responsible for the control of head and eye movements. However, neuroanatomical evidence of alterations in the head neural integrator in cervical dystonia is sparse.

Objectives

We investigated structural and functional integrity of the INC and its connections in cervical dystonia.

Methods

This cross-sectional, observational study compared 19 cervical dystonia patients and 21 healthy controls, using anatomical, diffusion-weighted, and resting-state functional images. We reconstructed tracts converging on the INC, and involved in the control of head movements. We evaluated

SUBMITTER: Zito GA 

PROVIDER: S-EPMC12661620 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature