Somato-Cognitive Action Network in Focal Dystonia.

ABSTRACT:

Background

The central pathology causing idiopathic focal dystonia remains unclear. The recently identified somato-cognitive action network (SCAN) has been implicated.

Objective

We tested whether the effector-agnostic SCAN may constitute a central pathology shared across dystonia subtypes, whereas the effector-specific regions in the primary sensorimotor cortex may show distinct functional changes specific to the dystonic body part.

Methods

We collected functional magnetic resonance imaging (MRI) from patients with focal dystonia (laryngeal dystonia [LD], N = 24; focal hand dystonia [FHD], N = 18) and healthy control participants (N = 21). Regions of interest were selected a priori within the basal ganglia-thalamo-cortical and cerebello-thalamo-cortical sensorimotor p

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12661636 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature