Association between stress hyperglycemia ratio and delirium risk in elderly surgical patients: a retrospective cohort study.

ABSTRACT:

Background

The stress hyperglycemia ratio (SHR) is an emerging glycemic marker in critical care, but its relationship with delirium in elderly surgical and trauma ICU patients remains unclear. This study explored the association between SHR and delirium to inform early identification strategies.

Methods

We performed a retrospective cohort study using the MIMIC-IV database, including 1,111 ICU patients aged ≥ 65 years with surgical or trauma admissions. SHR was calculated as the ratio of admission glucose to estimated average glucose (based on HbA1c) and categorized into quartiles. The primary outcome was ICU delirium, identified using the CAM-ICU tool; in-hospital mortality served as a secondary outcome. Multivariable logistic regression, restricted cubic spline (RCS) analys

SUBMITTER: Yao F 

PROVIDER: S-EPMC12661673 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature