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Persistence with topical glaucoma therapy in Japan from the perspective of product, formulation, and patient characteristics: analysis of medical insurance claim data.


ABSTRACT:

Background

Glaucoma is the leading cause of irreversible blindness in Japan and constitutes a serious public health challenge. Due to its asymptomatic onset and slow progression, patient persistence with topical glaucoma therapies remains low, significantly compromising treatment effectiveness. While some pharmaceutical companies have promoted disease awareness and improved eyedrop container usability, persistence may vary widely between products. However, no prior study in Japan has comprehensively examined persistence with antiglaucoma eyedrops by individual product or formulation characteristics. This study aimed to evaluate product-specific and formulation-specific persistence rates and identify patient factors associated with persistence, using large-scale Japanese medical ins

SUBMITTER: Kabeya K 

PROVIDER: S-EPMC12661687 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature