The long-term outcomes of radioactive iodine therapy in malignant struma ovarii with extensive abdominopelvic metastases: a case report and literature review.

ABSTRACT:

Background

Struma ovarii (SO) is a rare type of teratoma characterized predominantly by thyroid tissue, accounting for only 1% of all ovarian tumors and 2% of ovarian teratomas. Clinical presentation commonly includes abdominal pain or irregular menstrual cycles. While typically benign, SO may rarely undergo malignant transformation, occurring in an estimated 0.3% to 5.0% of cases. Most cases of malignant struma ovarii (MSO) are diagnosed postoperatively through histopathological examination or incidentally detected during abdominal ultrasound or computed tomography scans. Although MSO exhibits biological behavior analogous to thyroid carcinomas, considerable controversy persists regarding optimal surgical extent and postoperative management, reflecting its unpredictable clinical c

SUBMITTER: Cao J 

PROVIDER: S-EPMC12661863 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature