Association between NHHR and endometriosis and the mediating role of the CALLY index: a cross-sectional study based on NHANES.

ABSTRACT:

Background

The ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol (NHHR), a new lipid marker, can comprehensively reflect the lipid metabolic status of an individual. This study aimed to investigate the association between the NHHR and endometriosis, as well as the potential mediating role of a novel immuno-nutritional score, the C-reactive protein-albumin-lymphocyte (CALLY) index, in this relationship.

Methods

The National Health and Nutrition Examination Survey (NHANES) 2001-2006 data were utilized for analysis. The link between NHHR values and EMS prevalence was examined via the multivariable logistic regression (MLR) models. The dose-response association was assessed through restricted cubic spline models. The stability of the findi

SUBMITTER: Jing W 

PROVIDER: S-EPMC12661875 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature