Topical treatments for seasonal allergic conjunctivitis: systematic review and meta-analysis of efficacy and effectiveness.

ABSTRACT:

Background

Evidence for the effectiveness of topical treatments, in providing symptomatic relief from ocular allergy, remains uncertain.

Aims

To assess the effectiveness and relative efficacy of topical treatments for the management of seasonal allergic conjunctivitis.

Design of study

A systematic review and meta-analysis.

Setting

A literature search of the Cochrane Library, Medline, and EMBASE bibliographic databases.

Method

Double-masked randomised controlled trials were identified, that compared the use of topical mast cell stabilisers (sodium cromoglycate, nedocromil, lodoxamide) with placebo, topical antihistamines with placebo, and topical mast cell stabilisers with topical antihistamines.

Results

A meta-analysis of six trials showed that pa

SUBMITTER: Owen CG 

PROVIDER: S-EPMC1266207 | biostudies-literature | 2004 Jun

REPOSITORIES: biostudies-literature