Outcomes of adults with community-acquired bacterial meningitis in the Netherlands: a prospective nationwide cohort study.

ABSTRACT:

Background

Bacterial meningitis is associated with high rates of unfavourable outcome. We conducted a nationwide prospective study in the Netherlands to evaluate outcome in adults with bacterial meningitis, focusing on pathogen-specific differences, risk factors for unfavourable outcomes, and neurological sequelae.

Methods

Adult patients with community-acquired bacterial meningitis confirmed by lumbar puncture were identified through the database of the Netherlands Reference Laboratory for Bacterial Meningitis and prospectively included. Neurological examinations were performed on admission and discharge by the treating physician, and outcome was assessed using the Glasgow Outcome Scale, with scores of 1-4 classified as unfavourable. Logistic regression was used to evaluate

SUBMITTER: Drost EHGM 

PROVIDER: S-EPMC12662076 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature