The impacts of sarcopenia and its components on heart failure patients: A systematic review and network meta-analysis.

ABSTRACT:

Background

Heart failure (HF) and sarcopenia are prevalent, interrelated conditions that significantly impact older adults. Sarcopenia, characterized by progressive decline in muscle mass, strength, and function, is common in HF and linked to higher mortality, hospitalization, and functional decline. Early recognition is hindered by overlap with frailty, variability in assessment methods, and diagnostic challenges in fluid-overloaded patients. These challenges underscore the importance of clarifying the prognostic role of specific sarcopenia-related components in HF. This study aimed to assess which components related to sarcopenia are the strongest predictors of adverse outcomes in HF patients.

Methods

We systematically searched PubMed, Web of Science, Embase, and Scopus da

SUBMITTER: Tran TTQ 

PROVIDER: S-EPMC12662324 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature