Defining the <i>r</i> factor for post-trauma resilience and its neural predictors.

ABSTRACT: Although resilience is a dynamic process of recovery after trauma, in most studies it is conceptualized as the absence of specific psychopathology following trauma. Here, using the emergency department AURORA study (n = 1,835 with 63% women), we took a longitudinal, dynamic and transdiagnostic approach to define a static resilience (r) factor, which could explain greater than 50% of variance in mental well-being 6 months following trauma and a dynamic resilience factor, which represented recovery from initial symptoms. We then assessed its neurobiological profile across threat, inhibition and reward processes using functional magnetic resonance imaging collected 2 weeks post-trauma (n = 260). Our whole-brain and study-wide Bonferroni-corrected results suggest that resi

SUBMITTER: van Rooij SJH 

PROVIDER: S-EPMC12662592 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature