Risk factors and clinical prediction model for vertebral artery stenosis following radiotherapy for nasopharyngeal carcinoma.

ABSTRACT: ObjectiveThis retrospective cohort study aimed to investigate the independent risk factors for vertebral artery stenosis following radiotherapy for nasopharyngeal carcinoma and construct a nomogram-based prediction model to assess its clinical utility.MethodsIn total, 386 nasopharyngeal carcinoma patients who underwent radiotherapy at a tertiary hospital between 2017 and 2023 were included; the median follow-up duration was 23.3 (interquartile range, 12.5-33.7) months, and the incidence of vertebral artery stenosis was 29.8% (115/386). Univariate Cox regression analysis was used to identify factors associated with vertebral artery stenosis, followed by least absolute shrinkage and selection operator (LASSO) regression analyses to determine the key variables. Multivariate Cox regression was

SUBMITTER: Zhou J 

PROVIDER: S-EPMC12663071 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature