Reciprocal control of metabolic and chromatin regulators improves rice tolerance to heat.

ABSTRACT: Plant metabolic activities are regulated to adapt to the fluctuating environment for optimized growth, while interplay between metabolic and chromatin pathways plays an essential role in environmental adaptation. However, how metabolic and chromatin regulators cooperate to control metabolite accumulation and gene expression required for stress tolerance remains unclear. Here, we show that the pyruvate kinase 1 (PK1) has a function to integrate stress signals for metabolic and epigenetic controls of heat tolerance in rice. Over-expression of PK1 enhances plant tolerance to heat, while its loss-of-function decreases the recovery rate from heat stress. Heat stress induces PK1 production, nuclear enrichment, lysine acetylation and activity for pyruvate accumulation, H3T11 phosphorylation (H3T1

SUBMITTER: Yue Y 

PROVIDER: S-EPMC12663109 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature