Dynamics of postnatal upper airway bacteria colonization in preterm infants <1000g and bronchopulmonary dysplasia.

ABSTRACT: Aberrant microbial colonization of premature infants is increasingly recognized as a risk factor for severe acute morbidities. The aim of this study was to evaluate the correlation of bacterial upper airway colonization within the first 6 weeks of life in preterm infants <1000g and risk of moderate/severe bronchopulmonary dysplasia (BPD). In this retrospective two-center cohort study postnatal upper airway bacterial colonization of premature infants with a birth weight <1000g was analyzed. Bacteria were categorized into facultative- and highly pathogenic. Within 242 infants, a birth weight cutoff of 800g prevailed as the most relevant discriminator for risk of BPD. Furthermore, center, male sex, duration of antibiotic therapy, and delayed detection of facultative pathogenic bacteria after

SUBMITTER: Frodermann T 

PROVIDER: S-EPMC12663399 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature