Neighborhood socioeconomic status and overall survival among children with acute lymphoblastic leukemia.

ABSTRACT:

Abstract

A disadvantaged neighborhood, as represented by area-level socioeconomic status (SES), has been associated with adverse outcomes among children with acute lymphoblastic leukemia (ALL) in the United States, but the duration of impact after ALL diagnosis is not well understood. This retrospective cohort study used the National Cancer Database to evaluate the impact of area-level SES on overall survival among children with ALL. Median income and education quartiles based on residential zip code were used to create a composite area-level SES variable. Individual-level variables included age, sex, race, year of diagnosis, primary payer, distance to care, rurality, time to treatment, and comorbidity index. Cox proportional hazard models were created overall and conditional on su

SUBMITTER: Hoppmann AL 

PROVIDER: S-EPMC12663511 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature