A device for simultaneous neural recording and drug infusion in rodents.

ABSTRACT: Here we present and validate an open-source motorized swivel which allows simultaneous neural and behavioral recording from rodents during drug infusion experiments. Cable and drug line tangling represents a limiting factor for neural recordings in freely moving rodents. This limits the scope of experiments that can be carried out using currently available commutators. The proposed device offers a cost-effective solution to the problem of cable twisting and line tangling during experiments in freely moving rodents, enabling in vivo recordings for new experimental paradigms such as drug self-administration. Additionally, it requires minimal human supervision, simplifying the experimental design pipeline and facilitating scalability. To demonstrate the usefulness and functionality of the dev

SUBMITTER: Barbera G 

PROVIDER: S-EPMC12663644 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature