Retinal Morphology in Successfully Treated Macula-Off Retinal Detachment Based on Semiautomated Layer Quantification of High-Resolution Optical Coherence Tomography.

ABSTRACT:

Purpose

To evaluate retinal layer thickness (RLT) after retinal detachment (RD) using high-resolution (HighRes) optical coherence tomography (OCT).

Methods

This prospective, cross-sectional, observational study included 44 (out of 53; 14 [31.8%] female; mean age = 62 ± 10 years) patients with successfully treated macula-off RD. HighRes OCT and Spectralis OCT volume scans (97 scans; both Heidelberg Engineering GmbH, Heidelberg, Germany) were generated for study eyes (SEs) and healthy fellow eyes (FEs), followed by semiautomatic layer segmentation analysis.

Results

The thicknesses of the ganglion cell layer and inner plexiform layer (GCL-IPL) and inner nuclear layer (INL) were higher in SEs than in FEs (GCL-IPL: 64.4 ± 5.4 µm vs. 61.2 ± 5.2 µm, P < 0.001; INL: 35.1 ± 2.

SUBMITTER: Kreminger JE 

PROVIDER: S-EPMC12663895 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature