Exercise as a modulator of systemic inflammation and oxidative stress biomarkers across clinical and healthy populations: an umbrella meta-analysis.

ABSTRACT:

Objective

Inflammation is a condition that trigger an immune response and oxidative stress refers to an imbalance between production and elimination of reactive oxygen species (ROS). However, several non-pharmacological approaches have been proposed to improve health outcomes, among which exercise programs have shown promising effects on inflammatory and oxidative biomarkers across various health conditions.

Aim

In this regard, the present umbrella meta-analysis aimed to evaluate the potential of exercise interventions to modulate inflammatory and oxidative stress biomarkers across different population.

Methods

A comprehensive systematic search was carried out in on Scopus, PubMed, Embase, Web of Science, and Google Scholar up to March 2025. The overall effect size (E

SUBMITTER: Feng W 

PROVIDER: S-EPMC12664164 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature