Dietary supplementation with Bacillus-based probiotic improves gut health in the weaned piglets challenged by rotavirus.

ABSTRACT:

Background

As probiotics, Bacillus strains may regulate some physiological functions in animals. This study aimed to evaluate whether dietary supplementation with a Bacillus-based probiotic could alleviate gut damage induced by rotavirus (RV) infection in piglets. Twenty-four piglets were randomly assigned into 2 groups fed with the basal diet (n = 16) and the diet containing 10⁹ colony-forming unit Bacillus spores/kg (n = 8). On d 8, 8 piglets fed with the diet supplemented with Bacillus-based probiotic and 8 piglets fed with basal diet were orally infused with RV, while the residue piglets had oral gavage of sterile essential medium. The trial duration was 12 d.

Results

RV challenge induced diarrhea, significantly destroyed the morphology of jejunal mucosa (P < 

SUBMITTER: Xiang F 

PROVIDER: S-EPMC12664204 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature