A preliminary survey on the use of ART among blood donors in Shenzhen China and its implications to blood safety.

ABSTRACT:

Importance

The recent introduction of the AIDS pre-exposure or post-exposure prophylaxis (PrEP/PEP) medication has sparked fear of the possible increase of human immunodeficiency virus (HIV) and Treponema pallidum (TP) transfusion-transmission risk due to the potential administration of antiretroviral therapy (ART) in blood donors. However, the extent to which ART drugs are currently being utilized by blood donors in China remains to be clarified.

Objective

To assess the prevalence of ART drug use in individuals who attempted to donate blood but were eventually rejected due to anti-HIV and/or anti-Treponema pallidum (anti-TP) reactive in Shenzhen, China and to elucidate the characteristics of these high-risk cohorts using anonymised individual-level data.

Design

High

SUBMITTER: Wang L 

PROVIDER: S-EPMC12664271 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature