Cardiac autonomic function in patients with single ventricle physiology after Fontan palliation: A literature review.

ABSTRACT:

Background

The Fontan operation has significantly improved survival in patients with single ventricle physiology. This comes at a price of highly prevalent long-term complications. Autonomic dysfunction has been documented in patients after Fontan palliation. Although autonomic dysfunction is associated with a range of adverse outcomes, the exact clinical implications in patients with a Fontan circulation remain unclear.

Aims

The aims of this review are to address (1) the extent and characteristics of autonomic dysfunction in Fontan patients; (2) its association with clinical short- and long-term outcomes, and (3) identify key gaps in the literature.

Methods

A literature search was performed in PubMed using a dedicated query for single ventricle disease and cardiac au

SUBMITTER: Polyakova E 

PROVIDER: S-EPMC12664356 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature