Burden of diffuse myocardial fibrosis assessed by cardiac magnetic resonance in repaired tetralogy of Fallot: A systematic review and meta-analysis.

ABSTRACT:

Background

The assessment of myocardial fibrosis by cardiac magnetic resonance (CMR) in patients with repaired tetralogy of Fallot (rTOF) is not routinely performed, primarily due to technical challenges in measuring right ventricular native T1 and extracellular volume (ECV). Additionally, although native T1 can be assessed without contrast, offering broader applicability, its role in evaluating myocardial fibrosis in rTOF patients remains unclear.

Objectives

The aim of this systematic review and meta-analysis was to evaluate interstitial fibrosis in both the right and left ventricles using native T1 and ECV quantification in patients with rTOF.

Methods

This systematic review was conducted according to the 2020 PRISMA guidelines and was registered in PROSPERO. The Pub

SUBMITTER: Secco JCP 

PROVIDER: S-EPMC12664405 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature