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<i>Strongyloides stercoralis</i> hyperinfection with thrombosis: A systematic review of case reports.


ABSTRACT:

Background

Strongyloides stercoralis hyperinfection syndrome (SHS) is a severe complication of strongyloidiasis, typically in immunosuppressed patients. While sepsis and multiorgan dysfunction are well recognized, the association with thrombotic complications remains underexplored.

Methods

We conducted a systematic review of case reports and case series following PRISMA 2020 guidelines. PubMed, Embase, Scopus, Web of Science, and Google Scholar were searched through December 2024. Eligible studies included patients with SHS or disseminated strongyloidiasis and confirmed thrombotic events. Data on demographics, risk factors, infection characteristics, thrombosis, treatment, and outcomes were extracted and narratively synthesized.

Results

Fourteen studies describ

SUBMITTER: Lopez-Delgado DS 

PROVIDER: S-EPMC12664428 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature