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ABSTRACT: Background
Plant seeds constitute an important category of medicinal and edible herbs. However, assessments regarding their safety for human consumption remain insufficient. This systematic review comprehensively evaluates human safety for 21 medicinal and edible seeds.Methods
Two independent reviewers screened the titles, abstracts, and fulltexts of the retrieved literature against the inclusion and exclusion criteria to identify eligible AE reports in both English (PubMed, Embase, CENTRAL) and Chinese (CNKI, Wanfang, VIP, SinoMed) databases. Search strategies were constructed using the scientific names, common names, and frequent aliases of the medicinal and edible seeds combined with safety evaluation keywords such as "adverse reaction," "toxicity," and "side effect." An
SUBMITTER: Yuan L
PROVIDER: S-EPMC12664519 | biostudies-literature | 2026 Jun
REPOSITORIES: biostudies-literature