Type 1 Diabetes and Other Autoimmune Diseases-Epidemiology, Pathophysiology and Screening.

ABSTRACT:

Introduction

The interplay between type 1 diabetes (T1D) and concomitant autoimmune diseases (AID) is both clinically and scientifically relevant. In this review, we delineate the epidemiological, pathophysiological and practical aspects underlying polyautoimmunity with a focus on T1D.

Method

A comprehensive review of literature on T1D and associated AID was conducted, with the aim of drawing informed conclusions relevant to clinical practice. It draws on a targeted PubMed search conducted March-May 2025, emphasising recent peer-reviewed articles in English.

Results

Epidemiological data consistently indicate that individuals with T1D exhibit a significantly increased prevalence of additional AID. Familial aggregation of discordant AID and the concept of polyglandular

SUBMITTER: Kahaly GJ 

PROVIDER: S-EPMC12664531 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature