Transcatheter Versus Surgical Aortic Valve Replacement in Patients Aged 50 to 64 Years in the United States.

ABSTRACT:

Background

Outcomes of transcatheter aortic valve replacement (TAVR) vs surgical aortic valve replacement (SAVR) in patients aged 50-64 years have not been evaluated in randomized clinical trials. Despite the lack of randomized data, these patients are often treated with TAVR.

Methods

We queried the Nationwide Readmissions Database (2016-2021) to identify patients aged 50-64 years hospitalized for isolated aortic valve replacement (AVR). The contemporary use of TAVR and SAVR in patients aged 50-64 years was evaluated. In-hospital outcomes of TAVR vs SAVR were compared using propensity score matching. Readmissions were compared using the Cox proportional hazards regression model.

Results

Of 75,413 weighted hospitalizations for isolated AVR in patients aged 50-64 years,

SUBMITTER: Ismayl M 

PROVIDER: S-EPMC12664615 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature