Combining Optical Coherence Tomography and Fractional Flow Reserve for Decision Making in Percutaneous Coronary Intervention: Insights From the FUSION Study.

ABSTRACT:

Background

Physiological indices and intracoronary imaging provide additional and complementary information to coronary angiography, which may enhance procedural decision making during percutaneous coronary intervention (PCI). This study aimed to evaluate the impact of fractional flow reserve (FFR) and optical coherence tomography (OCT) on revascularization decision making and PCI strategy compared with angiography guidance alone.

Methods

In this secondary analysis from the prospective, observational FUSION (Validation of OCT-Based Functional Diagnosis of Coronary Stenosis) study, the impact of angiography, OCT, and FFR on procedural decision making was evaluated by comparing the intended treatment strategy after each step to the actual treatment strategy, which was left to

SUBMITTER: Volleberg RHJA 

PROVIDER: S-EPMC12664641 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature