Timing of starting anticoagulation following decompressive surgery for cerebral vein and sinus thrombosis: An observational study.

ABSTRACT:

Background

Anticoagulation is the mainstay acute therapy for cerebral venous thrombosis (CVT). Decompressive surgery is required in a small minority of patients with large parenchymal lesions and impending herniation, which requires a temporary suspension of anticoagulation.

Aim

The objective of this study was to identify the optimal timing for starting or resuming anticoagulation following decompressive surgery.

Methods

Data were collected from the Decompressive Surgery for CVT Study 2 (DECOMPRESS2), a prospective multinational cohort observational study of 118 patients with severe CVT treated by decompressive surgery. We assessed the frequency of new hemorrhagic and venous thrombotic events from admission to discharge in patients who started or resumed anticoagulati

SUBMITTER: Taveira MC 

PROVIDER: S-EPMC12664934 | biostudies-literature | 2025 Apr

REPOSITORIES: biostudies-literature