Role of Probiotics in Management of Depressive Symptoms and Cognitive Impairment in Patients With Depression: An Updated Analysis of Trials.

ABSTRACT:

Background and objective

Depression is a global burden that causes mortality and morbidity in patients and affects millions of people worldwide. Conventional treatment of depression has limited efficacy in addressing cognitive symptoms. Probiotics, particularly psychobiotics, offer promise by modulating the gut-brain axis and improving both depressive symptoms and cognitive function. This meta-analysis provides insights into the potential of probiotics in alleviating depression-related symptoms and cognitive deficits in comparison with placebo.

Method

A thorough literature search was performed using online resources such as PubMed, Embase, Cochrane, and Google Scholar. The seven randomized control trials (RCTs) met the inclusion criteria. The study was conducted in complianc

SUBMITTER: Arsal SA 

PROVIDER: S-EPMC12665043 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature