Morphological and functional aspects of the canine placental barrier: evidence supporting a deciduo-chorial model.

ABSTRACT:

Abstract

The canine placenta, characterized by its deciduate and endotheliochorial nature, represents an intermediate placental type between non-invasive and highly invasive placentae. Decidual cells are involved in the prepartum parturition cascade. As they are the only cells expressing the nuclear progesterone receptor (PGR), they play a crucial role in luteal progesterone (P4)-dependent embryo-maternal communication and are essential for maintaining pregnancy. This study focuses on the quantity, morphology, and spatial arrangement of decidual cells. Immunohistochemistry (IHC) was used to localize and quantify PGR-expressing cells. Consecutive tissue sections were evaluated utilizing anti-PGR, anti-vimentin, and anti-pan-cytokeratin antibodies, providing insights into decidual ce

SUBMITTER: Corte GM 

PROVIDER: S-EPMC12665514 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature