Effects of a pain oriented biobehavioral therapeutic education program on brain plasticity and pain intensity in subjects with chronic musculoskeletal pain: a feasibility study of a randomized controlled trial.

ABSTRACT:

Background

Chronic pain significantly impacts the physical, emotional, and social wellbeing of individuals. Despite advances in treatments, chronic pain prevalence continues to rise, emphasizing the need for comprehensive therapeutic approaches.

Objective

This study aimed to evaluate the feasibility and preliminary effects of a one-month Pain Oriented Biobehavioral Therapeutic Education (POBTE) program on clinical outcomes for chronic primary musculoskeletal pain.

Methods

In a single-blind feasibility pilot of a randomized controlled trial, 16 participants were assigned to an intervention group receiving POBTE education and exercise (n = 8) or a control group (n = 8) participating in exercise only. Primary outcomes were pain intensity, measured by the Nu

SUBMITTER: Di-Bonaventura S 

PROVIDER: S-EPMC12665784 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature