Bioprosthetic Valve Failure: Management Strategies in the Mitral Position.

ABSTRACT:

Background

Bioprosthetic valve failure is a growing clinical challenge, particularly in younger patients with comorbidities. Transcatheter valve-in-valve implantation is an alternative to redo surgery but may fail in cases of severe calcification or infection.

Case summary

A 37-year-old man with systemic lupus erythematosus and end-stage renal disease on hemodialysis presented with NYHA functional class III dyspnea. He had undergone mitral valve replacement (MVR) with a bioprosthetic valve 12 years before, followed by transcatheter mitral valve-in-valve (ViV) implantation 9 years later. Two years post-ViV, he developed recurrent severe mitral stenosis with a mean gradient of 24 mm Hg, extensive mitral annular calcification, and severe pulmonary hypertension.

Discussion

SUBMITTER: AlOtaiby K 

PROVIDER: S-EPMC12665850 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature