Association between salivary and blood hormone concentrations using an automated electrochemiluminescence immunoassay technique: Challenges and pitfalls.

ABSTRACT: Blood-based measures are considered the gold standard for evaluating steroid hormone concentrations, particularly for confirmation of hormone profiles in female-specific research. However, saliva sampling offers several advantages: it can be collected independently by participants, is less invasive and might be a more time- and cost-effective solution. This preliminary study explored associations between salivary and blood plasma hormone (oestrogen, progesterone and cortisol) concentrations using an automated electrochemiluminescence immunoassay technique. Eight healthy, physically active females with a regular natural menstrual cycle provided: (1) daily app-based menstrual tracking data; (2) daily saliva samples; and (3) two blood samples, each at different time points in the third to fif

SUBMITTER: Hardaker NJ 

PROVIDER: S-EPMC12665927 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature