Combined effects of normobaric hypoxia and cold on respiratory system responses to high-intensity exercise.

ABSTRACT: Cold temperatures (<-15°C) increase exercise-induced bronchoconstriction (EIB), while hypoxic-induced hyperventilation exacerbates respiratory muscle fatigue for a given exercising task. This study aimed to determine the individual and combined effects of cold and normobaric hypoxia on the respiratory system responses to high-intensity exercise. Fourteen trained male runners ( V̇O2max${{\dot{V}}_{{{{\mathrm{O}}}_2}{\mathrm{max}}}}$ : 64 ± 5 mL/kg/min) randomly performed an incremental cardiopulmonary exercise test (CPET) to volitional exhaustion under four environmental conditions: normothermic (18°C) normoxia ( FIO2${{F}_{{\mathrm{I}}{{{\mathrm{O}}}_2}}}$ : 20.9%) and hypoxia ( FIO2${{F}_{{\mathrm{I}}{{{\mathrm{O}}}_2}}}$ : 13.5%), and cold (-20°C) normoxia and hypoxia. Ventilatory respon

SUBMITTER: Callovini A 

PROVIDER: S-EPMC12665948 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature