Rheumatoid arthritis and risk of non-tuberculous mycobacterial pulmonary disease: a nationwide longitudinal cohort study.

ABSTRACT:

Background

Previous literature suggested that rheumatoid arthritis (RA) might be a risk factor for nontuberculous mycobacteria pulmonary disease (NTM-PD). However, longitudinal studies did not comprehensively consider potential confounders such as body mass index and smoking status. In addition, the impact of RA seropositivity has not been well elucidated. In this study, we aimed to evaluate the risk of incident NTM-PD in subjects with RA versus age-matched and sex-matched controls, while focusing on the impact of RA serologic status on this association.

Methods

From the Korean National Health Insurance Service data from 2010 to 2017, we identified 60 315 participants aged ≥20 years with RA and 301 575 without RA who were age-matched and sex-matched 1:5. The participants wer

SUBMITTER: Yang B 

PROVIDER: S-EPMC12666120 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature