Association between latent tuberculosis infection and assisted reproductive outcomes: a systematic review and meta-analysis.

ABSTRACT:

Objectives

Tuberculosis (TB) is a common cause of infertility in humans, especially in regions with high TB prevalence. However, the impact of latent TB infection (LTBI) on pregnancy outcomes following assisted reproduction in patients with infertility remains unclear. This systematic review and meta-analysis aimed to assess significant differences in pregnancy outcomes after assisted reproduction between infertile patients with and without LTBI.

Design

Systematic review and meta-analysis using the Grading of Recommendation, Assessment, Development and Evaluation approach.

Data sources

PubMed, Embase and Web of Science were searched from inception to 1 September 2025.

Eligibility criteria

Case-control or cohort studies comparing assisted reproduction outcomes b

SUBMITTER: Sheng Z 

PROVIDER: S-EPMC12666154 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature