Prevalence and predictive factors associated with sustained remission in SLE: a systematic review.

ABSTRACT:

Objective

The question of sustained remission in SLE has been highlighted recently following data published on the use of chimeric antigen receptor-T cell therapy in SLE. With the review, we wanted to investigate the prevalence of sustained remission of 2 years or more in SLE with the current available treatments and to assess the predictive factors associated with this state.

Methods

A systematic review of Embase via Ovid and Medline via Ovid was performed. We considered articles of adult patients with SLE that report the prevalence and/or the predictive factors of sustained remission in SLE. We considered that the latter state is sustained if it was for 2 years or more.

Results

20 studies were included for final review. The definition of remission was different betw

SUBMITTER: Abida R 

PROVIDER: S-EPMC12666172 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature