Associations between High Protein Intake and Cardiovascular Diseases by Age Groups: A Cohort Study.

ABSTRACT:

Background

The association between high protein intake and cardiovascular diseases (CVD) was conflicting and the role of age in this relationship was rarely studied. This study aimed to examine the association of high protein diet with the risk of CVD and the interaction of age in this association.

Methods

Participants from UK biobank (2007-2023) with at least 1 dietary questionnaire and without history of chronic diseases at baseline were included. High-protein diet was defined as protein intake ≥1.8 g·kg^-1·day^-1. The primary outcome was major adverse cardiovascular events (MACE). Cox regression analyses and restricted cubic spline (RCS) regression analyses were performed.

Results

Among 19420 participants, the median (IQR) age was 54 (14) years

SUBMITTER: Huang C 

PROVIDER: S-EPMC12666336 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature