Ontology highlight
ABSTRACT: Background
Mitral annular calcification (MAC) complicates transcatheter interventions for degenerative mitral regurgitation (DMR), particularly with small mitral valve orifice areas (MVOAs).Case summary
An 83-year-old woman with severe DMR, severe MAC, and MVOA of 3.8 cm2 presented post-heart failure hospitalization with declining function. High surgical risk and unfavorable transcatheter mitral valve replacement anatomy (neo-LVOT 0.30 cm2) limited options to transcatheter edge-to-edge repair (TEER). Using the Edwards PASCAL precision system and the "Crab-Walk" technique (independent leaflet clasp manipulation for MAC-related challenges), TEER reduced mitral regurgitation to mild (1+), with a 2 mmHg gradient at 3 months. The patient was weaned off oxyg
SUBMITTER: Abdelmalek J
PROVIDER: S-EPMC12666553 | biostudies-literature | 2025 Dec
REPOSITORIES: biostudies-literature