Epidemiology of Metabolic Dysfunction-Associated Steatotic Liver Disease in South Asian Ethnicities: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background and aims

People of South Asian ethnicities are at increased risk of metabolic syndrome, but the epidemiology of metabolic dysfunction-associated steatotic liver disease (MASLD) in this population remains poorly understood. This systematic review and meta-analysis assesses the prevalence, cross-sectional severity, and clinically relevant endpoints of MASLD in this group.

Methods

Studies from January 2002 to November 2023 across PubMed, Embase, Ovid, and Cochrane databases, meeting inclusion criteria, were included. We performed a random effects meta-analysis to calculate pooled prevalence and proportions.

Results

Sixty-two articles met inclusion criteria (n = 40 745). Fifty-three were based in India, 4 in Sri Lanka, 3 in Pakistan, and 2 in Bangladesh. The po

SUBMITTER: James M 

PROVIDER: S-EPMC12666614 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature