Herbal treatment of IBV-E. coli salpingitis establishment of a salpingitis model of layer chickens caused by co-infection of infectious bronchitis virus and Escherichia coli for the curative efficacy assessment of three Chinese herbal compounds.

ABSTRACT: Salpingitis is a common disease affecting production performance of layer chickens, with pathogenic microbial infections being one of the primary etiological factors. Clinically, Infectious bronchitis virus (IBV) and Escherichia coli (E. coli) can often be simultaneously isolated from cases of oviduct inflammation in laying hens. However, the specific roles played by these two pathogens in the occurrence of salpingitis remain unclear. In this study, IBV and E. coli were inoculated in laying hens via single and mixed infections in order to establish an salpingitis model, and its pathogenesis was investigated through transcriptome sequencing analysis. Furthermore, the therapeutic effects of three modified formulas on the salpingitis of layer chickens were assessed. Results demonstrated that

SUBMITTER: Xiang X 

PROVIDER: S-EPMC12666715 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature