Flow-Driver-Generated Synchronized Nasal Intermittent Positive-Pressure Ventilation Versus Biphasic Positive Airway Pressure After Extubation in Preterm Infants.

ABSTRACT:

Objective

To compare the efficacy and safety of flow-driver-generated synchronized nasal intermittent positive-pressure ventilation (SNIPPV) and biphasic positive airway pressure (BiPAP) after extubation in preterm infants.

Hypothesis

SNIPPV delivered via a flow-driver device improves post-extubation outcomes compared with non-synchronized BiPAP.

Study design

This single-center, retrospective, observational cohort study was conducted in the neonatal intensive care unit of Nagoya University Hospital, Nagoya, Japan.

Patient selection

Preterm infants born at < 34 weeks of gestation who underwent endotracheal ventilation after birth and were subsequently supported with either BiPAP (from October 2017 to March 2020) or SNIPPV (from April 2020 to September 2022) afte

SUBMITTER: Suzuki T 

PROVIDER: S-EPMC12666728 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature