Chromosome-level genome assembly of trypanosomatid parasite Lotmaria passim links chromosome duplication and divergence with infection of honey bees.

ABSTRACT:

Background

The protist family Trypanosomatidae includes parasites of insects, vertebrates, plants, and even other unicellular eukaryotes. The genomes of these species harbor clues to the evolution of parasitism, adaptation to new hosts, and infection of mammals. We present an analysis of a chromosome-level genome assembly of Lotmaria passim, the most prevalent known trypanosomatid of honey bees, linking genome sequence and organization to gene expression and infection of bees.

Results

The genome showed a high degree of synteny with assemblies of other trypanosomatids and especially to the closely related Leptomonas pyrrhocoris. It included four copies of chromosomes that shared ancestry with the tetrasomic Leishmania Chromosome 31 and are consistently supernumerary throughou

SUBMITTER: Nearman A 

PROVIDER: S-EPMC12667155 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature