The impact of intraoperative esketamine infusion on postoperative sleep in patients undergoing general surgery.

ABSTRACT:

Objective

Major abdominal surgery frequently induces circadian sleep-wake disturbances, characterized by increased daytime rapid eye movement (REM) sleep and prolonged nocturnal wakefulness. This study investigated the effects of perioperative continuous esketamine infusion (0.3 mg/kg/h) on postoperative sleep disturbance in patients under general anesthesia. Intraoperative electroencephalography (EEG) monitoring was implemented with focused analysis of relative wavelength frequencies.

Methods

. Patients undergoing surgery received a continuous intraoperative esketamine infusion at a dose of 0.3 mg/kg/h. Concurrent electroencephalography (EEG)monitoring was performed, with the analysis specifically focusing on relative power percentages of the EEG signal.Preoperatively, leve

SUBMITTER: Zhang M 

PROVIDER: S-EPMC12667177 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature