Population Attributable Fraction for Cognitive Impairment in Mexican American Older Adults.

ABSTRACT:

Background

The contribution of modifiable risk factors to cases of mild cognitive impairment (MCI) and Alzheimer's disease and related dementias (AD/ADRD) among Hispanic/Latin (a,o,x) adults is unclear.

Objective

To determine the population attributable fraction (PAF), the proportion of MCI and AD/ADRD cases that would be eliminated with elimination of modifiable risk factors.

Methods

This was a cross-sectional analysis nested within a prospective cohort study (2018 - 2023) of Mexican American older adults. Logistic regression estimated the odds of probable MCI or AD/ADRD (defined by education-specific cutoff scores on the Montreal Cognitive Assessment) associated with age, sex, education, medical comorbidities, cigarette smoking, and alcohol consumption. We calculate

SUBMITTER: Springer MV 

PROVIDER: S-EPMC12667309 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature