CLAE: A High-Fidelity Nanopore Sequencing Strategy for Read-Level Viral Variant Detection and Environmental RNA Virus Discovery.

ABSTRACT: High-fidelity (HF) long-read sequencing enables accurate profiling of microorganisms and pathogens at single-molecule resolution. However, current Oxford Nanopore Technologies (ONT)-a revolutionary platform offering real-time, portable sequencing at relatively low instrumental cost-suffer from severe read-length bias, limited accuracy (often

SUBMITTER: Yu H 

PROVIDER: S-EPMC12667459 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature