BROAD-NESS Uncovers Dual-Stream Mechanisms Underlying Predictive Coding in Auditory Memory Networks.

ABSTRACT: Whole-brain network dynamics are yet to be fully understood, particularly in the context of auditory memory and predictive coding. BROAD-NESS (BROADband brain Network Estimation via Source Separation), a novel pipeline for extracting broadband whole-brain networks from source-reconstructed MEG data is introduced. During auditory sequence recognition, BROAD-NESS identified two orthogonal networks centered on auditory cortices. The first, also encompassing medial cingulate, is primarily involved in processing sounds and shows consistent but less marked differences between experimental conditions. The second, involving hippocampus, anterior cingulate, insula, and inferior temporal regions, exhibits strong condition-dependent dynamics, reflecting engagement in confirmed predictions and predict

SUBMITTER: Bonetti L 

PROVIDER: S-EPMC12667469 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature