Serum zinc level independently predicts need for inpatient intubation among patients hospitalized with COVID-19: A prospective observational study.

ABSTRACT:

Background

The coronavirus disease 2019 (COVID-19) pandemic caused significant morbidity and mortality. Further study of modifiable factors influencing COVID-19 severity and outcomes continues to be necessary. Serum zinc levels may play a role in modulating COVID-19 virus replication and consequently influence clinical outcomes.

Methods

This was a prospective observational study of adult patients hospitalized with COVID-19 assessing the relationship between serum zinc levels and clinical outcomes. Serum zinc levels were measured within 7 days of admission. The primary outcome was the need for intubation at any time during inpatient stay. Secondary outcomes included hospital disposition and incidence of shock and acute kidney injury.

Results

Serum zinc levels could be

SUBMITTER: McPherson SW 

PROVIDER: S-EPMC12667602 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature