Neural mechanisms of handedness for precision drawing: hand-dependent engagement of cortical networks for bimanual control and tool use.

ABSTRACT: The neural mechanisms of handedness remain poorly understood, particularly for lateralized movements such as precision drawing. Using functional magnetic resonance imaging (fMRI), we examined how healthy adults and individuals with peripheral nerve injury (PNI) in their dominant hand performed a visually guided drawing task with each hand. We hypothesized that the left superior parietal lobule (SPL) supports drawing with either hand, and that individuals with PNI would recruit the same mechanisms as healthy adults.

Methods

33 Right-handed adults (23 healthy adults, 10 patients) underwent fMRI while performing a precision drawing task, alternating between the right hand (RH) and left hand (LH). LH>RH effects were examined across 20 regions of interest (12 a priori, 8 post hoc) using

SUBMITTER: Kapil N 

PROVIDER: S-EPMC12667916 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature